Trial intelligence / Profile preview

TrAVeRse: Acalabrutinib + Venetoclax + Rituximab in Treatment-Naïve Mantle Cell Lymphoma

2023-505205-16-00Phase 2Authorised

Sponsor
AstraZeneca
Start
Dec 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
7
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Overview

Phase 2, randomised, open-label trial of acalabrutinib, venetoclax and rituximab in mantle cell lymphoma (MCL) (2 arms), sponsored by AstraZeneca. Primary endpoint: MRD-negative complete response rate. Planned start Dec 2023; status: authorised.

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Drugs

acalabrutinibvenetoclaxrituximab
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Conditions

mantle cell lymphoma (MCL)

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