Trial intelligence / Profile preview

HOVON 171 AML: cobicistat-boosted venetoclax plus azacitidine in newly diagnosed AML unfit for intensive therapy

2023-505379-61-00Phase 2Suspended

Sponsor
HOVON
Start
Jan 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of venetoclax, cobicistat and azacitidine in acute myeloid leukemia (AML), sponsored by HOVON. Primary endpoints: Pharmacokinetic equivalence and Overall survival. Started Jan 2024; status: suspended.

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Drugs

venetoclaxcobicistatazacitidine
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Conditions

acute myeloid leukemia (AML)

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