Trial intelligence / Profile preview

LEAP-001 pembrolizumab + lenvatinib versus chemotherapy in first-line advanced or recurrent endometrial carcinoma

2023-505614-17-00Phase 3Completed

Sponsor
Merck & Co.
Start
Sep 2019
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
22
01

Overview

Phase 3, randomised, open-label trial in endometrial cancer (EC) comparing Keytruda + Lenvatinib with carboplatin + paclitaxel (2 arms). Primary endpoints: Progression-free survival and Overall survival. Started Sep 2019; status: completed.

02

Drugs

pembrolizumablenvatinibcarboplatinpaclitaxel
03

Conditions

endometrial cancer (EC)

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