Trial intelligence / Profile preview

Glofitamab dose-escalation and expansion study in relapsed/refractory B-cell non-Hodgkin lymphoma

2023-505625-14-00Phase 2Authorised

Sponsor
Roche
Start
Jan 2017
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
13
01

Overview

Phase 2, open-label trial of glofitamab in mature B-cell lymphoma, diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL) and 5 more (2 arms), sponsored by Roche. Primary endpoints: Incidence of dose-limiting toxicities, Primary safety endpoints and 11 more. Planned start Jan 2017; status: authorised.

02

Drugs

glofitamab
03

Conditions

mature B-cell lymphomadiffuse large B-cell lymphoma (DLBCL)follicular lymphoma (FL)mantle cell lymphoma (MCL)marginal zone B-cell lymphoma (MZL)

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Study design & results

Available in the Gosset platform where reported.

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