Trial intelligence / Profile preview

CaZa: zanubrutinib in primary cold agglutinin disease

2023-505746-25-00Phase 2Authorised

Sponsor
HOVON
Start
Apr 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
4
01

Overview

Phase 2, open-label, single-arm trial of zanubrutinib in cold agglutinin disease (CAD), sponsored by HOVON. Primary endpoint: CAD response rate after 6 cycles. Planned start Apr 2024; status: authorised.

02

Drugs

zanubrutinib
03

Conditions

cold agglutinin disease (CAD)

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