Trial intelligence / Profile preview

ERIKA neoadjuvant endocrine therapy trial in hormone receptor-positive HER2-negative early breast cancer

2023-505758-17-00Phase 2Authorised

Sponsor
Austrian Breast and Colorectal Cancer Study Group
Start
Aug 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Small Molecules
Countries
2
01

Overview

Phase 2, randomised, open-label trial of elacestrant, ribociclib, letrozole, anastrozole and exemestane in breast cancer (2 arms), sponsored by Austrian Breast and Colorectal Cancer Study Group. Primary endpoint: Proportion of modified PEPI score of 0 at surgery. Planned start Aug 2025; status: authorised.

02

Drugs

elacestrantribociclibletrozoleanastrozoleexemestane
03

Conditions

breast cancer

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