Trial intelligence / Profile preview

Acalabrutinib plus Venetoclax vs Venetoclax plus Obinutuzumab in Previously Untreated CLL/SLL

2023-505866-27-00Phase 3Authorised

Sponsor
AstraZeneca
Start
Mar 2024
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
7
01

Overview

Phase 3, randomised, open-label trial in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) comparing Acalabrutinib plus Venetoclax with Venetoclax plus Obinutuzumab (2 arms). Primary endpoint: Progression-free survival. Planned start Mar 2024; status: authorised.

02

Drugs

acalabrutinibvenetoclaxobinutuzumab
03

Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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