Trial intelligence / Profile preview

KEYNOTE-B99 first-line extensive-stage small cell lung cancer platform study

2023-506538-56-00Phase 2Completed

Sponsor
Merck & Co.
Start
Aug 2021
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
11
01

Overview

Phase 2, randomised, open-label trial in small cell lung cancer (SCLC) comparing Keytruda + lenvatinib + etoposide + platinum, Keytruda + MK-4830 + etoposide + platinum and Keytruda + boserolimab + etoposide + platinum (3 arms). Primary endpoints: Objective Response Rate and Six-month Progression-Free Survival. Started Aug 2021; status: completed.

02

Drugs

pembrolizumablenvatinibmk-4830boserolimab
03

Conditions

small cell lung cancer (SCLC)

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