Trial intelligence / Profile preview

Phase I/II [177Lu]Lu-NeoB plus capecitabine in GRPR-positive ER-positive HER2-negative metastatic breast cancer

2023-506717-21-00Phase 2Authorised

Sponsor
Novartis
Start
Apr 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
14
01

Overview

Phase 2, open-label trial of AAA503 and capecitabine in breast cancer (2 arms), sponsored by Novartis. Primary endpoints: Safety and tolerability and Antitumor activity and survival. Planned start Apr 2024; status: authorised.

02

Drugs

AAA503capecitabine
03

Conditions

breast cancer

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