Trial intelligence / Profile preview

KEYMAKER-U03 substudy 03B in second-line metastatic renal cell carcinoma

2023-506839-15-00Phase 2Completed

Sponsor
Merck & Co.
Start
Feb 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
15
01

Overview

Phase 2, randomised, open-label trial of pembrolizumab, lenvatinib, belzutifan, mk-4830, favezelimab and 1 more in renal cell carcinoma (RCC) (5 arms), sponsored by Merck & Co. Primary endpoints: Number of participants who experience one or more dose-limiting toxicities, Number of participants who experience one or more adverse events and 3 more. Started Feb 2024; status: completed.

02

Drugs

pembrolizumablenvatinibbelzutifanmk-4830favezelimab
03

Conditions

renal cell carcinoma (RCC)

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