Trial intelligence / Profile preview

KEYNOTE-991: Pembrolizumab Plus Enzalutamide Plus ADT in mHSPC

2023-507024-24-00Phase 3Completed

Sponsor
Merck & Co.
Start
Jan 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
22
01

Overview

Phase 3, randomised, double-blind trial in prostate cancer (PCa) comparing Pembrolizumab + enzalutamide + ADT with Placebo + enzalutamide + ADT (2 arms). Primary endpoints: Radiographic progression-free survival (rPFS) and Overall survival (OS). Started Jan 2024; status: completed.

02

Drugs

03

Conditions

prostate cancer (PCa)

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