Study design & results
Available in the Gosset platform where reported.
Trial intelligence / Profile preview
TACTIVE-U Sub-study C: Vepdegestrant (ARV-471) + Samuraciclib in ER+ Advanced or Metastatic Breast Cancer
2023-507125-41-00Phase 2Completed
- Sponsor
- Pfizer
- Start
- Mar 2024
- Modality
- Small Molecules, PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
- Countries
- 7
01
Overview
Phase 2, open-label trial of vepdegestrant and samuraciclib in breast cancer (2 arms), sponsored by Pfizer. Primary endpoints: Dose-limiting toxicities during DLT observation period (Cycle 1), Confirmed objective response rate and 2 more. Started Mar 2024; status: completed.
02
Drugs
vepdegestrantsamuraciclib
03
Conditions
breast cancer
Beyond the preview
Go deeper on 2023-507125-41-00.
Study design, results and competitive context are available in the Gosset platform where reported.
Competitive context
Available in the Gosset platform where reported.
Bring the full picture into focus.
See how Gosset can support your research on 2023-507125-41-00.