Trial intelligence / Profile preview

LIBRETTO-001 selpercatinib in RET-altered advanced solid tumors

2023-507702-13-00Phase 2Authorised

Sponsor
Loxo Oncology
Start
Sep 2017
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
16
01

Overview

Phase 2, open-label trial of selpercatinib in Nonhematologic neoplasms and Medullary Thyroid Cancer (MTC) (7 arms), sponsored by Loxo Oncology. Primary endpoints: Maximum tolerated dose / recommended Phase 2 dose and Objective response rate. Planned start Sep 2017; status: authorised.

02

Drugs

selpercatinib
03

Conditions

Nonhematologic neoplasmsMedullary Thyroid Cancer (MTC)

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