Trial intelligence / Profile preview

Efficacy of endothelin receptor antagonism in treatment of coronary artery spasm (EDIT-CAS)

2023-507782-25-00Phase 3Authorised

Sponsor
Radboud University Medical Center
Start
Sep 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised trial in Coronary vasospasm (CAS) and coronary functional abnormalities (CFA) comparing Bosentan with Placebo (2 arms). Primary endpoint: Absence of epicardial vasospasm at 10 weeks. Planned start Sep 2024; status: authorised.

02

Drugs

bosentan
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Conditions

Coronary vasospasm (CAS)coronary functional abnormalities (CFA)

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