Trial intelligence / Profile preview

CLARITY-Gastric 01

2023-508276-11-00Phase 3Authorised

Sponsor
AstraZeneca
Start
Jan 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
19
01

Overview

Phase 3, randomised, open-label trial of sonesitatug vedotin in gastric adenocarcinoma, gastroesophageal junction adenocarcinoma and esophageal adenocarcinoma (EAC) (2 arms), sponsored by AstraZeneca. Primary endpoints: Progression-free survival in all randomized participants and Overall survival in third-line or later participants. Planned start Jan 2025; status: authorised.

02

Drugs

sonesitatug vedotin
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinomaesophageal adenocarcinoma (EAC)

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Available in the Gosset platform where reported.

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