Trial intelligence / Profile preview

Phase 1/2 Study of DNL593 in Healthy Participants and Frontotemporal Dementia

2023-508697-28-00Phase 2Authorised

Sponsor
Denali Therapeutics Inc.
Start
May 2024
Modality
Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
11
01

Overview

Phase 2, randomised, double-blind trial of DNL593 in frontotemporal dementia (FTD) (5 arms), sponsored by Denali Therapeutics Inc. Primary endpoints: Incidence, severity, and seriousness of treatment-emergent adverse events and Change from baseline in safety assessments. Planned start May 2024; status: authorised.

02

Drugs

DNL593
03

Conditions

frontotemporal dementia (FTD)

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