Trial intelligence / Profile preview

EMERALD-3: Durvalumab + Tremelimumab ± Lenvatinib with TACE vs TACE Alone in Locoregional HCC

2023-508701-24-00Phase 3Authorised

Sponsor
AstraZeneca
Start
Apr 2024
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
21
01

Overview

Phase 3, randomised, open-label trial of durvalumab, tiragolumab and lenvatinib in hepatocellular carcinoma (HCC) (3 arms), sponsored by AstraZeneca. Primary endpoint: Progression-free survival. Planned start Apr 2024; status: authorised.

02

Drugs

durvalumabtiragolumablenvatinib
03

Conditions

hepatocellular carcinoma (HCC)

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