Trial intelligence / Profile preview

IMPAHCT-FUL

2023-508735-31-00Phase 3Completed

Sponsor
Aerovate Therapeutics
Start
Mar 2024
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
29
01

Overview

Phase 3, open-label, single-arm trial of 4-chlorokynurenine in pulmonary arterial hypertension (PAH), sponsored by Aerovate Therapeutics. Primary endpoints: Safety and tolerability of AV-101, Change from baseline in 6-minute walk distance (6MWD) and 3 more. Started Mar 2024; status: completed.

02

Drugs

4-chlorokynurenine
03

Conditions

pulmonary arterial hypertension (PAH)

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Available in the Gosset platform where reported.

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