Trial intelligence / Profile preview

BONFIRE beta-blocker discontinuation in heart failure with recovered ejection fraction

2023-508798-94-00Phase 3Authorised

Sponsor
Assistance publique - Hôpitaux de Paris
Start
Feb 2025
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of carvedilol, bisoprolol, metoprolol and nebivolol in heart failure (HF) (2 arms), sponsored by Assistance publique - Hôpitaux de Paris. Primary endpoint: Composite heart failure relapse endpoint. Planned start Feb 2025; status: authorised.

02

Drugs

carvedilolbisoprololmetoprololnebivolol
03

Conditions

heart failure (HF)

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