Trial intelligence / Profile preview

Asciminib versus investigator-selected TKI in newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase

2023-508838-33-00Phase 3Authorised

Sponsor
Novartis
Start
Oct 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
28
01

Overview

Phase 3, randomised, open-label trial of asciminib in chronic myelogenous leukemia (CML) (2 arms), sponsored by Novartis. Primary endpoint: Major Molecular Response at Week 48. Planned start Oct 2021; status: authorised.

02

Drugs

asciminib
03

Conditions

chronic myelogenous leukemia (CML)

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