Trial intelligence / Profile preview

EORTC 1740 in intermediate-risk HPV-positive locoregionally advanced oropharyngeal cancer

2023-508853-13-00Phase 2Authorised

Sponsor
European Organisation for Research and Treatment of Cancer
Start
Oct 2019
Modality
Small Molecules, PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
4
01

Overview

Phase 2, randomised, open-label trial of cisplatin, durvalumab and tremelimumab in oropharyngeal squamous cell carcinoma (OPSCC) (3 arms), sponsored by European Organisation for Research and Treatment of Cancer. Primary endpoint: Event-free survival. Planned start Oct 2019; status: authorised.

02

Drugs

cisplatindurvalumabtremelimumab
03

Conditions

oropharyngeal squamous cell carcinoma (OPSCC)

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