Trial intelligence / Profile preview

ALL2820: Ponatinib + Blinatumomab versus Chemotherapy + Imatinib in Newly Diagnosed Adult Ph+ ALL

2023-508968-30-00Phase 3Authorised

Sponsor
GIMEMA
Start
Sep 2021
Modality
Small Molecules, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, scFv Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 3, randomised, open-label trial in acute lymphoblastic leukemia (ALL) comparing Sequential ponatinib + blinatumomab with Chemotherapy + imatinib (2 arms). Primary endpoint: Event-free survival. Planned start Sep 2021; status: authorised.

02

Drugs

ponatinibblinatumomabimatinib
03

Conditions

acute lymphoblastic leukemia (ALL)

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Study design & results

Available in the Gosset platform where reported.

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