Trial intelligence / Profile preview

LuMIERE study of [177Lu]Lu-FAP-2286 in advanced solid tumors

2023-508995-12-01Phase 2Authorised

Sponsor
Novartis
Start
Dec 2025
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
Countries
7
01

Overview

Phase 2, open-label trial of AAA614 in breast cancer, non-small cell lung cancer (NSCLC) and pancreatic adenocarcinoma (PDAC) (5 arms), sponsored by Novartis. Primary endpoints: Objective response rate and Safety and tolerability. Planned start Dec 2025; status: authorised.

02

Drugs

AAA614
03

Conditions

breast cancernon-small cell lung cancer (NSCLC)pancreatic adenocarcinoma (PDAC)

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