Trial intelligence / Profile preview

EMERALD-1

2023-509053-32-00Phase 3Completed

Sponsor
AstraZeneca
Start
Feb 2024
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
18
01

Overview

Phase 3, randomised, double-blind trial in hepatocellular carcinoma (HCC) comparing Durvalumab + TACE, Durvalumab + bevacizumab + TACE and Placebo + TACE (3 arms). Primary endpoint: Progression-free survival (PFS). Started Feb 2024; status: completed.

02

Drugs

durvalumabbevacizumab
03

Conditions

hepatocellular carcinoma (HCC)

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Available in the Gosset platform where reported.

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