Trial intelligence / Profile preview

SHASTA-4 Study of plozasiran in adults with severe hypertriglyceridemia

2023-509301-80-00Phase 3Completed

Sponsor
Arrowhead Pharmaceuticals
Start
Nov 2024
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
17
01

Overview

Phase 3, randomised, double-blind trial in hypertriglyceridemia comparing Plozasiran with Placebo (2 arms). Primary endpoint: Percent change in fasting serum triglycerides at Month 12. Started Nov 2024; status: completed.

02

Drugs

plozasiran
03

Conditions

hypertriglyceridemia

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