Trial intelligence / Profile preview

Atezolizumab plus tiragolumab vs atezolizumab plus placebo in first-line PD-L1-positive recurrent/metastatic squamous cell carcinoma of the head and neck

2023-509449-10-00Phase 2Completed

Sponsor
Roche
Start
Jul 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
12
01

Overview

Phase 2, randomised, double-blind trial in head and neck squamous cell carcinoma (HNSCC) comparing Tecentriq + tiragolumab with Tecentriq + tiragolumab placebo (2 arms). Primary endpoint: Confirmed objective response rate. Started Jul 2024; status: completed.

02

Drugs

atezolizumabtiragolumab
03

Conditions

head and neck squamous cell carcinoma (HNSCC)

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