Trial intelligence / Profile preview

Phase I/II Study of DYP688 in Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

2023-509451-14-00Phase 2Suspended

Sponsor
Novartis
Start
Jul 2024
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
Countries
7
01

Overview

Phase 2, open-label trial of DYP688 in intraocular melanoma and melanoma (5 arms), sponsored by Novartis. Primary endpoints: Incidence and severity of dose limiting toxicities (DLTs), Incidence and severity of adverse events and serious adverse events (Phase I) and 2 more. Started Jul 2024; status: suspended.

02

Drugs

DYP688
03

Conditions

intraocular melanomamelanoma

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