Trial intelligence / Profile preview

LEE011 + BYL719 + letrozole in advanced ER-positive breast cancer

2023-509511-84-00Phase 2Authorised

Sponsor
Novartis
Start
Mar 2014
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
6
01

Overview

Phase 2, open-label trial of ribociclib, alpelisib and letrozole in breast cancer (5 arms), sponsored by Novartis. Primary endpoints: Incidence of dose-limiting toxicities in cycle 1, Safety and tolerability and 1 more. Planned start Mar 2014; status: authorised.

02

Drugs

ribociclibalpelisibletrozole
03

Conditions

breast cancer

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