Trial intelligence / Profile preview

RefIsh: encorafenib plus cetuximab rechallenge in BRAF V600E-mutant mCRC

2023-509564-22-00Phase 2Authorised

Sponsor
Vall d'Hebron Institute of Oncology
Start
Jul 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of encorafenib and cetuximab in colorectal cancer (CRC), sponsored by Vall d'Hebron Institute of Oncology. Primary endpoint: Progression-free survival rate at 4 months. Planned start Jul 2025; status: authorised.

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Drugs

encorafenibcetuximab
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Conditions

colorectal cancer (CRC)

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