Trial intelligence / Profile preview

Brainshuttle AD multiple-ascending dose study of RO7126209 (trontinemab) in prodromal or mild to moderate Alzheimer’s disease

2023-509678-52-00Phase 2Authorised

Sponsor
Roche
Start
Mar 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
12
01

Overview

Phase 2, randomised, double-blind trial in Alzheimer's disease (AD) comparing Trontinemab IV with Placebo IV (2 arms). Primary endpoints: Safety and tolerability of trontinemab (RO7126209) and Change from baseline in brain amyloid load (Part 3 primary). Planned start Mar 2024; status: authorised.

02

Drugs

trontinemab
03

Conditions

Alzheimer's disease (AD)

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