Trial intelligence / Profile preview

DOMENICA first-line trial in MMR-deficient advanced or recurrent endometrial cancer

2023-510097-14-00Phase 3Authorised

Sponsor
Arcagy-Gineco
Start
Apr 2022
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
10
01

Overview

Phase 3, randomised, open-label trial of dostarlimab, carboplatin and paclitaxel in endometrial adenocarcinoma (2 arms), sponsored by Arcagy-Gineco. Primary endpoint: Progression-free survival. Planned start Apr 2022; status: authorised.

02

Drugs

dostarlimabcarboplatinpaclitaxel
03

Conditions

endometrial adenocarcinoma

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