Trial intelligence / Profile preview

Pembrolizumab plus carboplatin/taxane induction followed by pembrolizumab with or without MK-2870 maintenance in metastatic squamous NSCLC

2023-510128-66-00Phase 3Authorised

Sponsor
Merck & Co.
Start
Aug 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
25
01

Overview

Phase 3, randomised trial in Pulmonary squamous cell carcinoma comparing Pembrolizumab + MK-2870 maintenance with Pembrolizumab maintenance (2 arms). Primary endpoint: Overall survival. Planned start Aug 2024; status: authorised.

02

Drugs

pembrolizumabsacituzumab tirumotecan
03

Conditions

Pulmonary squamous cell carcinoma

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Study design & results

Available in the Gosset platform where reported.

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