Trial intelligence / Profile preview

First-in-human dose-finding study of BMS-986470 in healthy volunteers and adults with sickle cell disease

2023-510283-12-00Phase 2Authorised

Sponsor
Bristol Myers Squibb
Start
Jun 2025
Modality
Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
4
01

Overview

Phase 2, randomised, double-blind trial in sickle cell disease (SCD) comparing BMS-986470 with Placebo (2 arms). Planned start Jun 2025; status: authorised.

02

Drugs

BMS-986470
03

Conditions

sickle cell disease (SCD)

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