Trial intelligence / Profile preview

Durvalumab ± Tremelimumab in Pediatric Advanced Malignancies

2023-510424-68-00Phase 2Authorised

Sponsor
AstraZeneca
Start
Jun 2024
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of durvalumab and tiragolumab in Nonhematologic neoplasms and hematopoietic malignancies (2 arms), sponsored by AstraZeneca. Primary endpoints: Adult equivalent exposure/MTD of durvalumab in combination with tremelimumab and durvalumab monotherapy, Safety and tolerability at adult equivalent exposure/MTD and 2 more. Planned start Jun 2024; status: authorised.

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Drugs

durvalumabtiragolumab
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Conditions

Nonhematologic neoplasmshematopoietic malignancies

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