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VIS trial: MRD-tailored first-line venetoclax + obinutuzumab with response-adapted venetoclax or venetoclax + zanubrutinib in young high-risk CLL

2023-510431-11-00Phase 2Authorised

Sponsor
GIMEMA
Start
Jul 2023
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of venetoclax, obinutuzumab and zanubrutinib in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) (3 arms), sponsored by GIMEMA. Planned start Jul 2023; status: authorised.

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Drugs

venetoclaxobinutuzumabzanubrutinib
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Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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