Trial intelligence / Profile preview

GRAPPA: PTCY vs ATG for graft-versus-host disease prophylaxis in unrelated donor PBSC transplantation

2023-510441-24-00Phase 3Completed

Sponsor
DKMS
Start
Sep 2024
Modality
Small Molecules, Recombinant Proteins and Enzymes, Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 3, randomised, open-label trial of cyclophosphamide and antithymocyte globulin rabbit in graft-versus-host disease (GVHD) (2 arms), sponsored by DKMS. Primary endpoints: Overall survival from randomization and Graft-versus-host disease-free and relapse-free survival. Started Sep 2024; status: completed.

02

Drugs

cyclophosphamideantithymocyte globulin rabbit
03

Conditions

graft-versus-host disease (GVHD)

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