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PEACE III: Enzalutamide vs Enzalutamide + Ra223 in mCRPC with Bone Metastases

2023-510453-41-00Phase 3Authorised

Sponsor
European Organisation for Research and Treatment of Cancer
Start
Jul 2024
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Alpha Emitters → Radiopharmaceuticals, Small Molecules
Countries
12
01

Overview

Phase 3, randomised trial in castration-resistant prostate cancer (CRPC) comparing Enzalutamide monotherapy with Enzalutamide + radium Ra 223 (2 arms). Primary endpoint: Radiological progression-free survival (rPFS1). Planned start Jul 2024; status: authorised.

02

Drugs

enzalutamideradium-223 dichloride
03

Conditions

castration-resistant prostate cancer (CRPC)

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