Trial intelligence / Profile preview

RESCUE-HUB

2023-510504-45-00Phase 2Authorised

Sponsor
Sant'Orsola-Malpighi University Hospital
Start
May 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of allogeneic fecal microbiota, atezolizumab and bevacizumab in hepatocellular carcinoma (HCC), sponsored by Sant'Orsola-Malpighi University Hospital. Primary endpoints: Incidence of grade >3 adverse events and Disease control rate at 12 weeks after fecal microbiota transplantation. Planned start May 2026; status: authorised.

02

Drugs

allogeneic fecal microbiotaatezolizumabbevacizumab
03

Conditions

hepatocellular carcinoma (HCC)

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