Trial intelligence / Profile preview

MERINO trial

2023-510523-30-00Phase 4Authorised

Sponsor
Diakonhjemmet Sykehus
Start
Feb 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 4, randomised, double-blind trial in erosive hand osteoarthritis (EHOA) comparing Methotrexate Pfizer with Placebo (2 arms). Primary endpoint: Difference in self-reported finger joint pain previous 48 hours on a visual analogue scale (VAS; 0-100 mm) at 6 months of treatment. Planned start Feb 2024; status: authorised.

02

Drugs

methotrexate
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Conditions

erosive hand osteoarthritis (EHOA)

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