Trial intelligence / Profile preview

Pucotenlimab + MRG003 versus MRG003 induction before chemoradiotherapy in locally advanced head and neck squamous cell carcinoma

2023-510558-18-00Phase 2Authorised

Sponsor
GORTEC
Start
Oct 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of pucotenlimab and becotatug vedotin in head and neck squamous cell carcinoma (HNSCC) (2 arms), sponsored by GORTEC. Primary endpoint: Best objective response rate. Planned start Oct 2025; status: authorised.

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Drugs

pucotenlimabbecotatug vedotin
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Conditions

head and neck squamous cell carcinoma (HNSCC)

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