Trial intelligence / Profile preview

VERDI: Venetoclax + Azacitidine for MRD-Positive AML Pre-alloHCT or Post-Chemotherapy

2024-510648-29-00Phase 3Authorised

Sponsor
CETLAM
Start
Aug 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, open-label, single-arm trial of venetoclax and azacitidine in acute myeloid leukemia (AML), sponsored by CETLAM. Primary endpoint: MRD conversion rate after 2 to 4 courses. Planned start Aug 2024; status: authorised.

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Drugs

venetoclaxazacitidine
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Conditions

acute myeloid leukemia (AML)

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