Trial intelligence / Profile preview

GEN1047 First-in-Human Dose Escalation and Expansion in Malignant Solid Tumors

2024-510722-10-00Phase 2Completed

Sponsor
Genmab
Start
May 2024
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
9
01

Overview

Phase 2, open-label, single-arm trial of GEN1047 in breast cancer, endometrial cancer (EC), ovarian cancer and 2 more, sponsored by Genmab. Primary endpoints: Dose-limiting toxicities (DLTs), Adverse events and safety laboratory parameters (Dose Escalation) and 1 more. Started May 2024; status: completed.

02

Drugs

GEN1047
03

Conditions

breast cancerendometrial cancer (EC)ovarian cancerPulmonary squamous cell carcinomaNon-hematologic malignancy

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