Trial intelligence / Profile preview

SGM-T1: SGM-101 tumor-targeted fluorescence endoscopy in rectal polyps with suspected T1 adenocarcinoma or high grade dysplasia

2024-510769-41-00Phase 2Completed

Sponsor
Leiden University Medical Center
Start
Oct 2024
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of sgm-101 in rectal cancer, rectal adenocarcinoma and colon adenoma, sponsored by Leiden University Medical Center. Primary endpoint: Primary ex-vivo NIR-fluorescence tumor-to-dysplasia ratio (TDR). Started Oct 2024; status: completed.

02

Drugs

sgm-101
03

Conditions

rectal cancerrectal adenocarcinomacolon adenoma

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