Trial intelligence / Profile preview

BRADI trial of bevacizumab versus placebo for corticosteroid-dependent or corticosteroid-resistant brain radionecrosis after radiotherapy for brain metastases

2024-510893-25-00Phase 3Authorised

Sponsor
Institut Cancérologique de l'Ouest
Start
Jun 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, double-blind trial in brain radionecrosis comparing Bevacizumab with Placebo (2 arms). Primary endpoints: Corticosteroid dose change and Neurologic function by NANO. Planned start Jun 2024; status: authorised.

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Drugs

bevacizumab
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Conditions

brain radionecrosis

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