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Asciminib versus nilotinib in newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase

2024-510947-71-00Phase 3Authorised

Sponsor
Novartis
Start
Jun 2024
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
24
01

Overview

Phase 3, randomised, open-label trial in chronic myelogenous leukemia (CML) comparing Asciminib with Nilotinib (2 arms). Primary endpoint: Time to discontinuation of study treatment due to adverse event. Planned start Jun 2024; status: authorised.

02

Drugs

asciminibnilotinib
03

Conditions

chronic myelogenous leukemia (CML)

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