Trial intelligence / Profile preview

PATROL study of azacitidine + venetoclax + tagraxofusp in higher-risk CMML

2024-511102-22-00Phase 2Authorised

Sponsor
GCP-Service International
Start
Mar 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
3
01

Overview

Phase 2, open-label, single-arm trial of azacitidine, venetoclax and tagraxofusp in chronic myelomonocytic leukemia (CMML), sponsored by GCP-Service International. Primary endpoints: Response rate after 3 cycles and Response assessment criteria. Planned start Mar 2025; status: authorised.

02

Drugs

azacitidinevenetoclaxtagraxofusp
03

Conditions

chronic myelomonocytic leukemia (CMML)

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