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DESTINY-Breast03: Trastuzumab deruxtecan vs T-DM1 in HER2-positive unresectable/metastatic breast cancer
2024-511204-16-00Phase 3Completed
- Sponsor
- Daiichi Sankyo Co., Ltd.
- Start
- May 2024
- Modality
- Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
- Countries
- 13
01
Overview
Phase 3, randomised, open-label trial of trastuzumab deruxtecan in breast cancer (2 arms), sponsored by Daiichi Sankyo Co., Ltd. Primary endpoint: Progression-free survival (PFS) by blinded independent central review. Started May 2024; status: completed.
02
Drugs
trastuzumab deruxtecan
03
Conditions
breast cancer
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Competitive context
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