Trial intelligence / Profile preview

Alectinib-based biomarker-selected perioperative/adjuvant therapy study in resectable ALK-positive non-small cell lung cancer

2024-511239-91-00Phase 2Completed

Sponsor
Roche
Start
Mar 2025
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
18
01

Overview

Phase 2, open-label trial of alectinib, pemetrexed, cisplatin and carboplatin in non-small cell lung cancer (NSCLC) (2 cohorts), sponsored by Roche. Primary endpoints: Adverse events and Investigator-assessed pathologic complete response. Started Mar 2025; status: completed.

02

Drugs

alectinibpemetrexedcisplatincarboplatin
03

Conditions

non-small cell lung cancer (NSCLC)

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