Trial intelligence / Profile preview

PITAC in malignant pleural effusion (MaPEPi)

2024-511255-17-00Phase 2Withdrawn

Sponsor
Azienda Ospedaliero-Universitaria Pisana
Start
Dec 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of cisplatin and doxorubicin in pleural carcinomatosis and malignant pleural effusion (MPE), sponsored by Azienda Ospedaliero-Universitaria Pisana. Primary endpoint: PITAC efficacy on pleurodesis and control of malignant pleural effusion volume. Planned start Dec 2025; status: withdrawn.

02

Drugs

cisplatindoxorubicin
03

Conditions

pleural carcinomatosismalignant pleural effusion (MPE)

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