Trial intelligence / Profile preview

PNOC029 Tovorafenib for Craniopharyngioma in Children and Young Adults

2024-511510-20-00Phase 2Authorised

Sponsor
Princess Máxima Center for Pediatric Oncology
Start
Mar 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
6
01

Overview

Phase 2, open-label trial of tovorafenib in craniopharyngioma (3 arms), sponsored by Princess Máxima Center for Pediatric Oncology. Primary endpoints: PFS12 and QOL12. Planned start Mar 2026; status: authorised.

02

Drugs

tovorafenib
03

Conditions

craniopharyngioma

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